CJC-1295 + Ipamorelin is a dual-peptide growth hormone secretagogue combination designed to
amplify endogenous Growth Hormone (GH) release while preserving the body's natural pulsatile and
feedback-regulated endocrine rhythm.
Rather than supplying GH directly, this pairing stimulates the pituitary gland through two
complementary physiological pathways-resulting in stronger, cleaner GH pulses with minimal off-
target effects.
CJC-1295 + Ipamorelin (10 Mg)
CJC-1295 - GHRH Pathway Activator
CJC-1295 is an analogue of Growth Hormone-Releasing Hormone (GHRH).
It acts at the hypothalamic-pituitary interface, binding to GHRH receptors on pituitary somatotrophs.
Its primary role:- Increases GH pulse amplitude
- Extends the duration of GH release
- Enhances pituitary responsiveness to natural stimuli (sleep, exercise)
It represents the "permission signal" for GH secretion.
Ipamorelin - Ghrelin (GHS) Pathway Activator
Ipamorelin is a selective ghrelin receptor (GHS-R) agonist.
Its defining features:- Triggers GH release via a separate receptor system
- Extremely selective for GH (minimal cortisol or prolactin activity)
- Mimics the body's natural ghrelin-induced GH pulses
Ipamorelin provides the "trigger signal" that initiates each pulse.
