Growth Hormone (GH) is a peptide hormone synthesized and secreted by the anterior pituitary gland, functioning as one of the body's most influential regulators of growth, metabolism, and structural maintenance. Unlike hormones that act continuously, GH is released in pulsatile waves, a feature that is essential to its biological potency and precision
Growth Hormone (36iu)
GH secretion follows a circadian rhythm, with its most pronounced pulses occurring during deep slow-wave sleep. Its release is finely regulated by the hypothalamus through two opposing signals:
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Growth Hormone–Releasing Hormone (GHRH) → stimulates GH secretion
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Somatostatin → inhibits GH release
Additional physiological stimuli that enhance GH release include:
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Intense physical exercise
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Fasting and caloric deficit
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Hypoglycemia
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Acute stress
This pulsatile and stimulus-dependent pattern prevents receptor desensitization and ensures maximal biological efficiency.
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