Semaglutide is a long-acting synthetic peptide belonging to the class of GLP-1 receptor agonists (Glucagon-Like Peptide-1 receptor agonists). It is engineered to mimic the physiological actions of the endogenous incretin hormone GLP-1, while exhibiting far greater stability, potency, and duration of action. Rather than functioning as a simple appetite suppressant, semaglutide acts as a central metabolic regulator, influencing appetite control, glucose homeostasis, and energy balance through coordinated neuro-endocrine pathways.
Semaglutide (10 Mg)
GLP-1 is a gut-derived hormone released primarily from intestinal L-cells in response to food intake. Its biological purpose is to act as a satiety and glucose-regulating signal, linking nutrient ingestion to metabolic response.
Native GLP-1:
- Reduces hunger signals in the brain.
- Enhances glucose-dependent insulin secretion
- Slows gastric emptying .
- Suppresses glucagon release
However, natural GLP-1 is rapidly degraded (half-life of minutes), limiting its therapeutic utility. Semaglutide overcomes this limitation.
